- ISO 17025 lab-tested
- 99%+ purity
- Research use only
PE 22-28 10mg
-
Processed as soon as payment clears
Packed and dispatched without delay.
-
Free shipping over €99.00 to most EU countries
-
Shipment protection included
Lost or damaged in transit? We send a replacement.
-
Discreet packaging
Plain parcel, no product names on the outside.
-
We accept
Secure checkout
- SEPA bank transfer
Independent lab results
Tested before it reaches your bench
Every batch is analysed by an independent, ISO 17025-accredited laboratory before release. The report shown here belongs to the batch now shipping, so what you read is what you receive.
Analiza Białek sp. z o.o.
ISO/IEC 17025 accredited
HPLC purity
99%
Release minimum: 99%
- Lot
- EP10/012026
- Tested
- July 2, 2026
- Measured
- 10.63 mg
- Report no.
- 12FR57HK
- Batch-specific
- Independent lab
Quality control results
1 passed · 1 reported-
Purity
Reversed-phase HPLC
99% Pass -
Net peptide content
HPLC quantitation
10.63 mg Reported
Tests in our panel
- Visual inspection · Colour, form and integrity of the lyophilised powder and the vial seal, checked against the specification.
- LC-MS · Confirms the molecular mass matches the expected structure of the compound.
- Impurity profile · Checks for residues from synthesis and handling that should not be present.
- Elemental analysis · Screens for toxic metals that can enter through raw materials or equipment.
- Microbial culture · Checks a sample for bacterial and fungal growth.
- Endotoxin assay · Measures bacterial endotoxins, reported in endotoxin units (EU) per vial.
All published batches
Every lot of this product we have released, each with its own certificate. Newest first.
PE 22-28 10mg
LatestLOT EP10/012026
99%
HPLC purity
- Measured content
- 10.63 mg
- Tested on
- July 2, 2026
2 assays by Analiza Białek sp. z o.o.
Open certificateTechnical specifications
Compound at a glance
Molecular profile
PE 22-28 10mg
- Compound class
- TREK-1 channel modulator (spadin-derived)
- Amino acids
- 7 aa
- Research area
- Mood & neuroplasticity research
Handling
Storage and stability
- −20 °C as powder
- 2–8 °C in solution
- Protect from light
- Keep dry
Lyophilised powder
−20 °C, protected from light and moisture
In solution
2 to 8 °C
General guidance for laboratory storage. Follow your institution’s handling procedures.
About this compound
PE-22-28 – Proenkephalin-Derived Neuropeptide Research Compound
- Composition: PE-22-28 (10 mg lyophilized peptide powder)
- Category: Peptide
- Form: 10 mg vial with freeze-dried powder
What is PE-22-28?
PE-22-28 is a synthetic neuropeptide fragment derived from Proenkephalin A, an endogenous precursor protein involved in opioid and neuroregulatory signaling pathways.
This peptide has been studied for its role in central nervous system modulation, particularly in relation to dopaminergic balance, prolactin regulation, and neuroendocrine signaling.
Unlike classical opioid peptides, PE-22-28 demonstrates non-analgesic, regulatory activity, making it a distinct compound within neuropeptide research.
In research settings, PE-22-28 (10 mg) is investigated for its influence on neurotransmitter regulation, motivational signaling, and hypothalamic-pituitary interactions.
Ideal for neuropeptide research, CNS signaling studies, and neuroendocrine pathway investigations.
Key Research Findings
Neuroregulatory Activity: Studied for its modulatory role within central neurotransmitter systems.
Dopaminergic Interaction: Associated with regulation of dopamine-linked signaling pathways in experimental models.
Prolactin Modulation Research: Investigated for its influence on prolactin-related neuroendocrine mechanisms.
Non-Opioid Functional Profile: Does not exhibit classical opioid receptor agonism.
CNS-Specific Interest: Primarily relevant to central rather than peripheral research models.
Mechanism of Action
PE-22-28 is believed to exert its effects through central neuroregulatory mechanisms, including:
- Neurotransmitter Modulation → Interaction with dopaminergic and neuroendocrine signaling circuits
- Hypothalamic Pathway Influence → Modulation of pituitary-related signaling cascades
- Receptor-Mediated Regulation → Indirect interaction with CNS receptor systems
- Central Activity Profile → Focused effects within the central nervous system
Storage Instructions
- Store at 2–8 °C (36–46 °F)
- Protect from light and moisture
- Do not freeze
- Use reconstituted solution within 2–3 weeks
Why Choose PE-22-28 (10 mg)?
PE-22-28 is valued in research environments for its unique position within proenkephalin-derived neuropeptides, offering insight into dopamine-regulated and prolactin-associated neuroendocrine pathways without direct opioid effects.
Its specificity and central activity profile make it particularly relevant for advanced CNS research, neuropeptide signaling studies, and hypothalamic-pituitary axis investigations.
Order PE-22-28 (10 mg) and explore its potential in advanced neuropeptide research, CNS signaling analysis, and neuroendocrine investigations.
Research notice
For laboratory research use only. This product is not a medicinal product or a food. It is not intended for human or veterinary use, or for any diagnostic or therapeutic purpose.
The buyer is responsible for receiving, storing, handling and disposing of this material safely and lawfully, in line with the rules of their country and institution. We sell only to adults aged 18 or over who are qualified to work with research materials.
Descriptions on this page summarise published research for educational purposes. They are not medical advice and make no claim about safety or effects in humans.
