Glutathione 1500mg

Glutathione (GSH) – Cellular Antioxidant & Redox Support

• Composition: Reduced L-Glutathione (lyophilized powder)
• Category: Antioxidant tripeptide
• Form: Vial with freeze-dried powder
• Application: Laboratory research following reconstitution according to the applicable research protocol

What is Glutathione?

Glutathione, commonly abbreviated as GSH, is a naturally occurring tripeptide composed of the amino acids glutamate, cysteine, and glycine.

It is present in nearly all human cells and plays a central role in antioxidant defense, cellular redox balance, detoxification pathways, and the protection of proteins, lipids, and DNA from oxidative damage.

Glutathione occurs primarily in its reduced form, GSH, and its oxidized form, GSSG. The relationship between these two forms is widely used in research as an indicator of cellular oxidative stress and redox status.

Ideal for antioxidant research, redox-biology studies, oxidative-stress models, and advanced cellular-protection research.

Key Research Findings

Antioxidant Defense: Glutathione helps neutralize reactive oxygen species and supports cellular protection against oxidative damage.

Redox Homeostasis: The GSH/GSSG system is essential for maintaining a balanced intracellular redox environment.

Detoxification Pathways: Glutathione participates in the conjugation and processing of reactive metabolites and other compounds.

Cellular Protection: Supports the protection of proteins, membranes, and genetic material from oxidation in experimental models.

Mitochondrial Function: Mitochondrial glutathione contributes to peroxide metabolism and the maintenance of mitochondrial integrity.

Enzyme Support: Functions as a substrate or cofactor within systems involving glutathione peroxidase, glutathione reductase, and glutathione transferases.

Mechanism of Action

Glutathione influences several fundamental cellular processes, including:

• Reactive Oxygen Species Neutralization → Helps reduce oxidative damage within cellular systems
• Glutathione Peroxidase Activity → Supports the conversion of hydrogen peroxide and lipid peroxides into less reactive products
• GSH/GSSG Redox Cycling → Maintains intracellular redox balance through reversible oxidation and regeneration
• Conjugation Reactions → Participates in glutathione-transferase-mediated processing of reactive compounds
• Protein Thiol Protection → Helps preserve the structure and activity of redox-sensitive proteins
• Mitochondrial Defense → Supports mitochondrial peroxide metabolism and membrane integrity

Research Application

Reconstitute according to the requirements of the applicable laboratory protocol.

There is no universal research concentration or exposure duration. The required amount should be determined by the specific in-vitro, analytical, or preclinical study design.

The vial is suitable for oxidative-stress experiments, antioxidant assays, redox measurements, and investigations of glutathione-dependent enzyme systems.

Following reconstitution, storage conditions and permitted usage time should be based on validated stability data and the batch-specific documentation.

Storage Instructions

• Store lyophilized material at 2–8 °C (36–46 °F)
• Protect from light, heat, air, and moisture
• Minimize repeated temperature fluctuations
• Avoid unnecessary exposure to oxygen after reconstitution
• Do not freeze unless supported by validated stability data
• Follow the batch-specific certificate and laboratory protocol

Why Choose Glutathione?

Glutathione is one of the most important endogenous compounds used in research into antioxidant defense, cellular redox regulation, mitochondrial protection, and oxidative stress.

Unlike experimental peptides that act through a narrowly defined receptor pathway, glutathione participates in numerous fundamental biochemical systems throughout the cell.

Because products intended for sterile research can be affected by contamination, oxidation, and elevated endotoxin levels, batch-specific testing for identity, purity, sterility, and endotoxins is particularly important.

Order Glutathione and explore its role in advanced antioxidant, redox-biology, and cellular-protection research.